We are a research lab in the Department of Pathobiological Sciences at the University of Wisconsin—Madison. We pair experimental and computational approaches to study neglected parasitic diseases and host-pathogen interactions, with the goal of identifying molecular drivers of successful infection. Our mission is to illuminate the biology of these complex pathogens, advance human and animal health through new therapeutics, and facilitate the training of scientists at every career stage.

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Lab News
Apr 2026 Congrats to Katie Ryan for a successful PhD defense!
Apr 2026 Dante is awarded an NSF GRFP Award!
Dec 2025 Dante James will join the lab as a PhD student in the MDTP program co-advised by Nancy Keller.
Nov 2025 Cole Knuese successfully defended his dissertation!
Jul 2025 Work on orotopical bat rabies vaccine led by Cole Knuese profiled in Science Magazine.
Jun 2025 Congrats to Clair Henthorn for completing her PhD! Clair is now a Scientist at PPD (Thermo Fisher).
Jun 2024 Katie and Natalia presented at AAVP in St. Louis. Katie won the Best Student Oral Presentation Award!
Sep 2024 Natalia Betancourt joins the lab as a PhD student through the CBMS program.
Jul 2024 Clair, Elena, and Katie presented talks and posters at the AAVP Meeting in Atlanta and took home presentation awards.
Aug 2023 Kendra has successfully defended her PhD and will be starting a postdoc at UC-Berkeley. Congrats Dr. Dahmer!
Jul 2023 New paper on Mansonella diagnostics and epidemiology in the Colombian Amazon.
Jun 2023 The lab helped host and presented posters at Mol Helm 2023 in Madison.
Apr 2023 Two new preprints resulting from Elena Rehborg and Lenny Nunn's undergrad projects.
Mar 2023 Welcome to GHI Postdoctoral Fellow Sebastián Díaz! Sebastian will be stationed in Medellin, Colombia.
Sep 2022 New preprint led by Clair using a single-cell atlas to investigate secretory behaviors and drug targets.
Sep 2022 New preprint led by Kendra on muscarinic receptors as anthelmintic targets.
Aug 2022 Monica joins us as a GHI Visiting Scholar.
Aug 2022 Kendra, Clair, and Katie presented their work at the Midwest Neglected Infectious Disease Meeting at Notre Dame.
Jul 2022 New preprint led by Nic on multivariate screening for macrofilaricide discovery.
May 2022 New preprint and software package for image-based phenotyping of parasites.
Apr 2022 Dr. Monica Palma-Cuero is awarded a GHI Visiting Scholar award.
Apr 2022 Spatial transcriptomics paper appears in PLoS Pathogens.
Jan 2022 Nic Wheeler has accepted an Assistant Professor position at UW-Eau Claire starting in the Fall.
Oct 2021 JB Collins joins us as a postdoc on an anthelmintic resistance project jointly mentored through Northwestern University.
Aug 2021 New preprint on spatial transcriptomics and antiparasitic target prioritization in a human filarial parasite.
Jun 2021 Opinion piece on high-content anthelmintic screening now out in Trends in Parasitology.
Mar 2021 Kendra receives an Honorable Mention for the Ford Foundation Predoctoral Fellowship.
Dec 2020 Nic awarded an NIH F32 fellowship to study parasite sensory behaviors.
Dec 2020 Katie Ryan joins our lab as a PhD student through the CMP program.
Dec 2020 Collaboration on ivermectin modulation of parasite vesicle release appears in the Journal of Extracellular Vesicles.
Nov 2020 Filarial long-read RNAseq paper appears in PLOS NTD.
Nov 2020 Kendra, Nic, and Mostafa present posters and talks at the 2020 ASTMH Annual Meeting.
Jun 2020 Preprint on long-read RNA-Seq in human and animal filarial parasites now online.
Jun 2020 Paper on sensory behaviors of parasites that cause lymphatic filariasis in press at PLoS Biology.
May 2020 The lab receives Global Health Institute grant to study filarial parasites infecting indigenous populations in Amazonia.
May 2020 Elena receives Honorable Mention for the UW Sophomore Research Fellowship.
Mar 2020 Clair Henthorn joins us as a CBMS PhD student.
Feb 2020 The lab receives NIH/NIAID R01 to study parasite secretory function and new strategies to disrupt host-parasite interactions.
Dec 2019 Review on schistosome vector control and gene drive potential is published.
Sep 2019 Paul presents poster and talk at the BSP / ISP joint meeting in Belfast; won 1st place poster prize.
Sep 2019 Kendra is appointed to the NIH PVB T32 training grant.
Sep 2019 Nic will be giving an invited talk at the PacBio North America User Group Meeting.
Jun 2019 New preprint on filarial chemosensory biology available on bioRxiv.
Jun 2019 We wish our first cohort of lab undergrads success in their journeys ahead! Eric Chen (NIH IRTA Fellow), Alexis Mann (PhD, Johns Hopkins), Katie Kudrna (DVM, UW-Madison).
May 2019 Nathalie Dinguirard joins us from the Yoshino Lab as a joint research specialist.
Apr 2019 Eric, Tran, and Katie present posters at UW Undergraduate Research Symposium.
Apr 2019 Kendra receives 2019 NSF GRFP Honorable Mention.
Feb 2019 The lab is excited to share our latest work at the upcoming Molecular Helminthology and WAAVP 2019 meetings.
Oct 2018 Large-scale helminth genomics effort appears in Nature Genetics. Our lab contributed primary analyses of potentially druggable GPCRs and ion channels.
Sep 2018 New preprint with Bartholomay & Kimber labs on chemosensation in filarial parasites.
Sep 2018 Kendra joins the lab as a CBMS PhD student. Abdi, Gabi, and Nick join us as undergrad researchers.
Sep 2018 Collaboration on the Bge cell line is published.
Aug 2018 Nic presents at the 15th International Symposium on Schistosomiasis in Rio de Janeiro.
Jul 2018 Zach joins the lab as a research intern.
Jul 2018 Paul Airs joins the lab as a Postdoc.
May 2018 Kathy Vaccaro joins the lab as a Research Specialist.
Apr 2018 Paper on stage and sex-specific differences in Brugia exosome cargo in press at PLoS NTD.
Apr 2018 Benzimidazole paper appears in PLoS NTD.
Dec 2017 Lab contributes to BioRxiv preprint on comparative genomics of major helminths.
Oct 2017 BioRxiv preprint on the discovery of genetic loci underlying benzimidazole resistance.
Oct 2017 Lab receives funding from NCVP / AHS.
Aug 2017 Alexis joins the lab as an Honorary Research Fellow.
Aug 2017 Contribution to Nature Communications paper on the genetics of a phoretic behavior.
May 2017 Nic joins the lab as a Merck KGaA Postdoc Fellow.
May 2017 Justice joins the lab as an Undergrad Lab Assistant.
Mar 2017 Lab receives NIH/NIAID K22 Phase II Award.
Feb 2017 Divyaa joins the lab as a joint Research Intern.
Feb 2017 Eric joins as an Undergraduate Researcher.
Feb 2017 Troy joins the lab as a Research Specialist.
Jan 2017 The lab officially opens.
Madison
School of Veterinary Medicine
Lab group

Past & present funding
NIH NSF WARF Gates Foundation USDA